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Cell Membrane
 *Nageli and Cramer first discover cell membrane in 1855
*Plowe named the cell membrane in 1931.

 Origin-
The outer layer of cytoplasm converted into cell membrane

 Appearance-
*Observe under electron microscope as trilaminar means it has three layer
*Outer and inner part is is electron dense layer or dark layer
*Middle part is electron less layer or transparent layer.

Structure of cell membrane-
*Gorter & Grendel-1926- 2 layerd lipid-protein model 
*Danielli(1935) & Schmitt (1940)-3 layerd protein lipid model
*Daneielli & Davison (1934,52,70) -2 layed lipid surrounded with 2 layed protein layerd
*Robertson(1959) protein-lipid-protein,3 layed unit membrane.

 Composition
*Lipids(20-79%)
*Protein (20-70%)
*Carbohydrate (1-5%)
*water(20%) 

Example:RBC
Protein-52%
Lipids-40%

Important component of plasma membrane
*Lipids-
Phospholipid, sterol, cholesterol, glycolipid spingolipid,etc
*Carbohydrates-
Branched and unbranched oligosaccharide
*Enzymes-
Almost 30 type of enzyme present,like phosphatases, ATPase, esterase, Nuclease etc.

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